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Showing posts from March, 2018

The Long Shot

I don't even know where to begin as my head is still spinning with the news I received today.  So I'm just going to put it out into the ether: Entyvio (vedolizumab), which I started for my Crohn's disease about 6 months ago, did what no other approach has:  cleared my eosinophilic esophagitis.  But wait, isn't Entyvio a drug for inflammatory bowel disease?   Yes. Is Eosinophilic Esophagitis a type of inflammatory bowel disease?   Nope. Are IBD and EoE related at all?   As far as we know today, no.  There are very few overlapping cases. So WTF happened? Without getting into the biomechanics of a drug that's way over my pay grade in medical understanding, my gastroenterologist had a theory that the way Entyvio works would block the cascade of eosinophils (a part of your immune system, a type of white blood cell) through it's magical way of selectively keeping my immune system from attacking my digestive tract. She was fucking right. Since being dia